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KMID : 0644319960020010001
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Journal of Korean Oriental Oncology
1996 Volume.2 No. 1 p.1 ~ p.23
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黃奎東
柳逢夏/朴東源/柳基遠
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Abstract
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ln order to research thc effects of Shipjundaebotang(SDT) and Oroachys Herba(OH) on anti-tumor and immune response, the author performed this experimental study.
Experimental groups are divided into five groups. which are solid extract of Oroachys Herba by water(OHM), soid extract
of Orostachys Herba by ethanol(OHE), solid extrad of Shipjundaebotang (SDT), solid extract of Shipjundaebotang added by solid cxtract of Orostaclys Herba by water(SDT+OHW) and solid cxtract of Shipjundaebotang added by solid extract of Orostachys Herba by ethanol (SDT+OHE).
In these experimental studies, extension of survival days for anti-tumor effect was observed. and delayed typ hypersensitivity and rosette forming cell for ceil-mediated immune response, hemagglutinin titers and hemolysin titers for humeral immune response, spleenic natural killer cell activity and carbon clearance (Kindex) in vitro were measured with mice.
The result were summerized as follows:
l. SDT, SDT+OHW and SDT+OHE treated groups were significantly recognized to extend the sunival days of tumor hearing mice as compared with the control group.
2. Delayed type topersensitivity was significantly increased in SDT, SDT+OHW and SDT+OHE treated groups as compared with control group.
3 Hemagglutinin titer was increared in all sample groups as compared with control group. but not significantly.
4. Hemolysin titers was significantly increased in SDT. SDT+OHW and SDT+OHE treatcd groups as compared with control group. and SDT+OHE treated group showed the increasing effect with significance as compared with the other sample groups.
5. For thc effect of rosette forming cell quantitation, SDT, SDT+OHW and SDT+OHE treated groups showed the increasing effcet with significance as compared with control group.
6. Natural kiner cell activity was significantly increased in SDT+OHW as compared with control group. but the omer groups, except OHW and SDT+OHW treated groups. revealed thc inaeasing effect as compared with control group, but thc significance was not admittcd.
7. For the effect of K-index(Carbon cleannce), SDT, SDT+OHW and SDT+OHE treated groups showd the increasing effect with significance as compared with control group.
8. The study didn´t show that Orostachys. herba had any significance with survival days. anti-tumor effect and immune response.
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KEYWORD
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